Researchers discover critical process for how breast cancer spreads in bones

April 30, 2018; Scientists Laurie Littlepage works with graduate student Ricardo Romero Moreno in her lab at the Harper Cancer Research Institute. (Photo by Barbara Johnston/University of Notre Dame)

Once breast cancer spreads to bone, options for treatment are limited. Breast cancer cells can lie dormant in the bone, often undetectable and able to escape typical treatments. Unfortunately, these dormant cells can awaken at any time to generate tumors. All of this combined makes it difficult to understand how the cells proliferate and how to stop them from doing so.

However, researchers from the University of Notre Dame have now identified a pair of proteins believed to be critical for spreading, or metastasizing, breast cancer to bone.

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October 7, 2019

Health and SocietyScience and TechnologyBiological SciencesBreast CancerCancerCollege of Sciencedigest153Harper Cancer Research InstituteHealthLaurie LittlepageMedicineResearch